Sepsis prediction models perform poorly when transferred between ICUs due to demographic and practice variation, leading to substantial performance drops caused by differences in patient populations, admission criteria, and data recording standards, which limits reliable deployment across healthcare systems. Retraining models from scratch requires large labeled datasets that many ICUs lack due to cost, time, and resource limitations, making it difficult for low-resource settings to develop or adopt effective predictive tools. We propose a meta-learning approach that enables rapid adaptation of sepsis prediction models using few-shot local data, leveraging pre-training across multiple ICUs to support fast personalization in new environments. The framework includes meta-training across diverse source ICUs to learn a generalizable initialization and meta-adaptation at the target ICU using only a few gradient updates on limited data, enabling efficient few-shot learning. This approach improves sepsis prediction in low-resource and heterogeneous ICU settings by reducing data requirements and increasing robustness to demographic shifts, supporting more equitable access to AI tools in critical care. The proposed framework enables efficient and fair deployment of sepsis prediction models across diverse ICUs, bridging resource gaps and improving scalability and adaptability of clinical AI systems globally.