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A Conceptual Early Warning Intelligence Framework for Sepsis-Aware ICU Monitoring Systems
Sepsis remains a critical determinant of mortality and resource utilization in intensive care units (ICUs), necessitating proactive, intelligence-driven monitoring architectures that transcend reactive vital-sign thresholds. This conceptual manuscript introduces the sepsis-aware early warning intelligence lattice (SAEWIL), a novel theoretical framework for orchestrating multi-layered artificial intelligence within ICU monitoring ecosystems. Grounded exclusively in architectural, infrastructural, and governance principles, SAEWIL integrates clinical AI system designs, electronic health record (EHR) intelligence ecosystems, decision support pipelines, interoperability frameworks, and human–AI workflow models to enable continuous, sepsis-aware situational awareness. The framework’s unique lattice topology features five interdependent layers connected by bidirectional feedback loops that dynamically propagate risk signals while embedding real-time governance and drift-sensitivity controls. Conceptual formulas formalize risk propagation, decision confidence, and monitoring burden, offering interpretive lenses for system designers and policymakers. By synthesizing high-impact literature from 2017–2021 on AI deployment in critical care, the manuscript delineates a scalable blueprint that prioritizes ethical orchestration, seamless clinical integration, and adaptive resilience without empirical performance claims. SAEWIL thus provides a foundational reference for next-generation sepsis-aware ICU intelligence infrastructures that align technological capability with clinical safety and operational sustainability.
Journal of Artificial Intelligence for Healthcare Systems
Original Research | Open access | 20 January 2022 | Article: 2

Rule-Augmented Artificial Intelligence Framework for Detecting Clinically Significant Abnormal Laboratory Result Patterns in Hospitalized Adults Using Sequential Blood Chemistry Panels, Vital Sign Trends, and Physician Response Times
Inpatient laboratory monitoring produces frequent blood chemistry results that must be reviewed in relation to the patient’s evolving clinical state. Although many results are statistically abnormal, only a smaller subset require urgent interpretation, escalation, or therapeutic action. Conventional rule-based critical value systems depend heavily on fixed thresholds and may generate non-actionable notifications. Pure machine-learning classifiers may detect complex patterns but can be difficult to explain, audit, or align with institutional clinical policies. This article proposes a rule-augmented artificial intelligence framework for detecting clinically significant abnormal laboratory result patterns in hospitalized adults. The framework uses established clinical logic as a structured skeleton and enriches it with sequential laboratory patterns, vital sign trends, and physician response-time feedback. The framework contains a clinical rule knowledge base, a sequential blood chemistry encoder, a vital sign fusion module, and a significance calibration layer. Together, these components would support interpretable pattern detection while allowing alert thresholds to adapt to observed clinical behavior. The proposed architecture could reduce non-actionable alerts by distinguishing isolated statistical abnormalities from evolving clinical patterns. It would also be expected to support patient-specific baselines and integrate into existing inpatient electronic health record workflows. A rule-augmented AI framework offers a pathway toward safer, smarter, and less disruptive laboratory result surveillance. Its value would depend on careful rule curation, transparent model governance, and prospective evaluation in real clinical settings.
Journal of Health Informatics and Digital Systems
Original Research | Open access | 25 February 2021 | Article: 64

Artificial Intelligence Framework for Real-Time Prioritization of Inpatient Transport Requests Using Patient Acuity, Destination Urgency, Transporter Availability, Elevator Congestion, and Unit-Level Transfer Demand
Inpatient transport is a critical but often under-recognized component of hospital operations. Delays in moving patients between wards, diagnostic areas, procedural suites, and discharge locations can disrupt clinical schedules, prolong waiting, and expose vulnerable patients to avoidable risk. Many hospital transport workflows still rely on first-in-first-out queues, dispatcher judgment, or simple proximity-based assignment. These approaches may overlook patient acuity, destination urgency, transporter workload, elevator congestion, and anticipated surges in unit-level demand. This article proposes an AI systems framework that continuously assigns a dynamic priority score to each inpatient transport request. The framework integrates patient acuity, destination urgency, transporter availability, elevator congestion, and forecasted unit-level transfer demand into a real-time dispatch logic. The framework includes a patient acuity stratification module, destination urgency classifier, transporter tracking layer, elevator congestion model, unit-level demand forecaster, and real-time prioritization engine. These components would operate as an integrated decision-support system rather than as isolated scheduling tools. The framework could support safer and more responsive transport decisions by aligning dispatch priority with both clinical risk and operational constraints. It would be expected to improve coordination among transporters, nursing units, procedural areas, and hospital command centers. A real-time AI transport prioritization framework offers a pathway toward more intelligent inpatient logistics. Its value should be evaluated through phased implementation, transparent governance, and careful assessment of clinical and operational consequences.
Journal of Health Informatics and Digital Systems
Original Research | Open access | 25 February 2023 | Article: 79
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AI-driven Diagnostics Artificial Intelligence in Health Informatics Artificial Intelligence in Healthcare Big Data in Healthcare Clinical Data Mining Clinical Decision Support Systems Clinical Informatics Computer Vision Connected Health Systems Deep Learning Digital Health Digital Healthcare Innovation Digital Transformation in Healthcare Electronic Health Records Ethical AI in Healthcare Explainable AI Health Data Analytics Health Data Privacy Health Informatics Health Information Management Health Information Systems Health System Optimization Health Technology Assessment Healthcare Data Science Healthcare Informatics Healthcare Information Security Healthcare Management Healthcare Management Information Systems Intelligent Medical Systems Internet of Medical Things (IoMT) Interoperability in Healthcare Systems Machine Learning Medical Data Analytics Medical Data Management Medical Imaging Mobile Health (mHealth) Natural Language Processing Precision Medicine Predictive Analytics Remote Patient Monitoring Smart Healthcare Systems Telemedicine Wearable Health Technologies e-Health




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