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Explainable Gradient Boosting Machine for Predicting Postpartum Hemorrhage Risk Using Intrapartum Electronic Fetal Monitoring, Maternal Vital Signs, and Labor Progression Data
Postpartum hemorrhage (PPH) is the leading cause of maternal mortality worldwide, accounting for 25–30% of deaths, particularly in low-resource settings, and early identification of high-risk patients during labor could enable timely interventions such as uterotonic administration, blood preparation, and escalation of care; however, current risk stratification models rely mainly on static antepartum factors and fail to incorporate dynamic intrapartum physiological changes. Existing tools, including those from the California Maternal Quality Care Collaborative, use baseline maternal characteristics such as prior PPH, BMI, parity, and comorbidities, but do not capture continuously evolving labor data, despite intrapartum signals like fetal heart rate patterns, maternal vital sign trends, and labor progression metrics containing rich predictive information that remains underused in real-time decision-making, while clinical judgment is limited by inter-observer variability and inability to integrate complex temporal trends. To address this gap, we propose an explainable gradient boosting machine framework for real-time PPH risk prediction that integrates electronic fetal monitoring parameters (baseline rate, variability, decelerations), maternal vital signs (heart rate, blood pressure, temperature, oxygen saturation), and labor progression features (cervical dilation, contraction frequency, stage duration, and oxytocin use), producing continuously updated risk scores throughout labor. The system combines a gradient boosting model (XGBoost or LightGBM), a SHAP-based explainability module, a real-time feature extraction pipeline, and a clinician-facing dashboard that displays risk scores and key contributing factors, where SHAP provides both global and patient-specific interpretability by identifying how features such as tachysystole or prolonged labor stages influence predictions, thereby improving transparency and clinical trust. Overall, this framework enables dynamic, interpretable PPH risk assessment using routinely collected intrapartum data, combining predictive accuracy with explainability to support earlier detection of hemorrhage risk and more timely, targeted interventions.
Journal of Artificial Intelligence for Healthcare Systems
Original Research | Open access | 20 January 2026 | Article: 117

Explainable Gradient Boosting Framework for Identifying Key Drivers of Delayed Emergency Department Discharge Using Diagnostic Order Completion Times, Bed Availability, Consultant Response Delays, and Patient Acuity Scores
Emergency department discharge delays are a critical operational bottleneck shaped by diagnostic completion intervals, inpatient bed scarcity, consultant responsiveness, and patient acuity. Understanding these drivers in real time is essential for improving flow and reducing avoidable crowding. Current ED analytics often describe aggregate delays after they occur. Clinicians and operational managers therefore lack transparent patient-level tools that indicate which factor is most responsible for a specific delayed discharge episode. This article proposes an explainable gradient-boosting framework for identifying key contributors to delayed ED discharge. The framework focuses on diagnostic order completion times, bed availability, consultant response delays, and patient acuity scores. The proposed framework uses a gradient-boosted tree ensemble trained on historical ED visit data and paired with SHAP-based post-hoc explanations. It is designed conceptually for real-time use with live electronic health record, bed-board, order, and consultation data. Conceptually, the framework would generate both a delay-risk score and an interpretable decomposition of that risk. These explanations could support targeted actions such as expediting a pending diagnostic test, escalating bed-management review, or re-contacting a delayed consultant service. The framework would shift ED discharge management from reactive reporting toward proactive operational decision support. Explainability is positioned as the foundation for clinician trust, workflow alignment, and accountable deployment.
Journal of Health Informatics and Digital Systems
Original Research | Open access | 25 February 2022 | Article: 67

Explainable Gradient Boosting Model for Predicting Health Insurance Claim Denials Using Documentation Completeness, Procedure Codes, Diagnosis-Code Consistency, Payer Rules, and Prior Authorization History
Claim denials represent a major source of lost or delayed healthcare revenue. They are commonly driven by documentation gaps, coding inconsistencies, payer rule violations, and missing or invalid prior authorizations. Current denial prevention often depends on manual review and deterministic claim-scrubbing rules. These approaches may not capture complex payer-specific interactions among documentation quality, procedure codes, diagnosis codes, and authorization history. This article proposes an explainable gradient boosting model for estimating the probability that a health insurance claim could be denied before submission. The model is intended to identify the specific claim-level factors contributing to denial risk. The proposed framework uses a gradient-boosted tree ensemble trained conceptually on historical claims and remittance data. SHAP-based explanations would provide both global and local interpretability for denial-risk predictions. Conceptually, the model would return a denial risk score alongside an explanation of contributing factors such as incomplete documentation, diagnosis-code mismatch, expired authorization, or payer rule conflict. These outputs would support targeted pre-billing review rather than broad manual auditing. An explainable denial prediction model could help shift revenue cycle management from reactive appeals toward proactive prevention. Transparent reasoning would be essential for revenue cycle staff, clinical documentation teams, coders, and compliance stakeholders.
Journal of Health Informatics and Digital Systems
Original Research | Open access | 20 July 2023 | Article: 80
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AI-driven Diagnostics Artificial Intelligence in Health Informatics Artificial Intelligence in Healthcare Big Data in Healthcare Clinical Data Mining Clinical Decision Support Systems Clinical Informatics Computer Vision Connected Health Systems Deep Learning Digital Health Digital Healthcare Innovation Digital Transformation in Healthcare Electronic Health Records Ethical AI in Healthcare Explainable AI Health Data Analytics Health Data Privacy Health Informatics Health Information Management Health Information Systems Health System Optimization Health Technology Assessment Healthcare Data Science Healthcare Informatics Healthcare Information Security Healthcare Management Healthcare Management Information Systems Intelligent Medical Systems Internet of Medical Things (IoMT) Interoperability in Healthcare Systems Machine Learning Medical Data Analytics Medical Data Management Medical Imaging Mobile Health (mHealth) Natural Language Processing Precision Medicine Predictive Analytics Remote Patient Monitoring Smart Healthcare Systems Telemedicine Wearable Health Technologies e-Health




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