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Artificial Intelligence for Hospital Workflow Analytics: A Systematic Review of Machine Learning Models for Patient Flow, Staff Scheduling, Resource Utilization, and Operational Delay Prediction
Hospital workflow analytics has become central to improving throughput, reducing operational cost, and strengthening patient experience. Artificial intelligence offers predictive capabilities for patient flow, staffing, resource use, and delay anticipation. This systematic review examined machine learning models applied to patient flow, staff scheduling, resource utilisation, and operational delay prediction in hospital settings. The review focused on model types, operational endpoints, data sources, validation methods, and implementation maturity. A PRISMA 2020-aligned search strategy was designed for PubMed, Scopus, IEEE Xplore, and Web of Science. Screening, extraction, risk-of-bias appraisal, and narrative synthesis were structured around hospital operations rather than clinical diagnosis. The literature was dominated by retrospective, single-centre studies focused on patient flow, especially length-of-stay, admission, discharge, and bed-use prediction. Staffing, resource utilisation, and operational delay prediction were less frequently studied, and prospective deployment remained uncommon. Machine learning for hospital operations is maturing technically but remains fragmented across isolated workflow domains. Integration across patient flow, staffing, resource utilisation, and delay management requires stronger prospective evaluation.
Journal of Health Informatics and Digital Systems
Review | Open access | 25 February 2021 | Article: 65

Machine Learning for Hospital Length-of-Stay Prediction: A Systematic Review of Electronic Health Record Features, Model Architectures, Validation Methods, and Operational Implementation Outcomes
Hospital length-of-stay is a central operational metric for inpatient capacity planning, discharge coordination, and resource allocation. Accurate prediction remains difficult because patient trajectories are heterogeneous, nonlinear, and shaped by evolving clinical events during admission. Traditional statistical models often have limited flexibility for high-dimensional and sequential electronic health record data. Across the literature, there is no settled consensus regarding optimal model architecture, feature representation, validation design, or clinical implementation strategy. This systematic review synthesizes machine learning approaches for hospital length-of-stay prediction published from 2017 to 2022. It focuses on EHR feature types, model architectures, validation methods, interpretability strategies, and reported operational outcomes. A structured review of peer-reviewed literature was conducted using targeted search strings related to machine learning, deep learning, electronic health records, discharge prediction, and hospital length-of-stay. The review included studies across emergency, inpatient, surgical, pediatric, cardiovascular, and intensive care settings. The literature suggests that gradient boosting, random forest, ensemble learning, and recurrent neural networks are common approaches for LOS prediction. However, external validation remains uncommon, prediction horizons vary widely, and operational implementation outcomes are reported less consistently than model development results. Future research should prioritize external validation, prospective implementation studies, standardized outcome definitions, and transparent reporting of workflow barriers. Shared benchmarking datasets and multi-center validation consortia would strengthen comparability across LOS prediction studies.
Journal of Health Informatics and Digital Systems
Review | Open access | 25 February 2023 | Article: 75

Explainable Machine Learning in Healthcare Administration: A Systematic Review of Transparency Methods for Operational Decision Support, Revenue Cycle Analytics, and Quality Monitoring
Machine learning is increasingly used in hospital operations, revenue cycle management, and quality monitoring. These administrative applications require transparency because their outputs can influence access, resource allocation, financial decisions, and accountability. This systematic review examined explainable machine learning methods applied to operational decision support, revenue cycle analytics, and quality monitoring in healthcare administration. The review focused on the type, depth, and use of transparency methods rather than predictive performance. A PRISMA 2020–compliant search strategy was applied to PubMed, Scopus, IEEE Xplore, and Web of Science for studies published between 2017 and 2022. Screening, extraction, and narrative synthesis focused on administrative domain, model type, explanation method, stakeholder use, and risk of bias. SHAP and LIME were the most frequently discussed post-hoc explanation approaches, while feature importance, partial dependence, rule-based models, and attention mechanisms appeared in smaller subsets of the literature. Operational decision support showed the strongest explainability uptake, whereas revenue cycle analytics and administrative quality monitoring remained less developed. Explainability in healthcare administration remains uneven and often superficial. The largest gap is not the availability of explanation tools, but the limited evidence that explanations improve managerial decisions, accountability, fairness, or auditability.
Journal of Health Informatics and Digital Systems
Review | Open access | 25 February 2023 | Article: 77

Artificial Intelligence for Clinical Documentation Improvement from 2017 to 2023: A Systematic Review of Natural Language Processing Methods for Coding Accuracy, Note Quality, Billing Support, and Physician Workflow Efficiency
Clinical documentation is central to continuity of care, coding, billing, compliance, and quality measurement, yet it remains a major source of administrative burden for physicians. Artificial intelligence, especially natural language processing, has been proposed as a way to improve documentation quality, coding accuracy, billing support, and clinical workflow efficiency. This systematic review synthesised evidence from 2017 to 2023 on natural language processing methods applied to clinical documentation improvement. The review focused on automated clinical coding, note quality, billing support, computer-assisted physician documentation, and physician workflow efficiency. A PRISMA 2020-compliant search strategy was applied to PubMed, Scopus, IEEE Xplore, and Web of Science for publications from 1 January 2017 to 31 December 2023. Screening was performed in duplicate, and eligible studies were narratively synthesised by documentation domain, model type, deployment maturity, and evaluation approach. The evidence base expanded rapidly during the review period, especially in automated coding and clinical note generation. Several studies reported technically promising systems for ICD coding, documentation summarisation, and speech-derived notes, whereas billing outcomes and sustained workflow effects were less commonly evaluated. Natural language processing for clinical documentation improvement appears most mature for automated coding and note analysis. Evidence for billing support and physician workflow transformation remains less developed, particularly in prospective clinical environments.
Journal of Health Informatics and Digital Systems
Review | Open access | 25 February 2024 | Article: 88

Machine Learning for Healthcare Revenue Cycle Analytics: A Systematic Review of Claim Denial Prediction, Coding Automation, Payment Delay Forecasting, and Prior Authorization Support
Revenue cycle inefficiencies, including claim denials, coding errors, delayed reimbursement, and prior authorization workload, impose substantial administrative and financial burdens on healthcare organizations. Machine learning has been proposed as a decision-support approach for improving prediction, automation, and workflow prioritization in these areas. This systematic review examined peer-reviewed and closely related scholarly literature from 2017 to 2023 on machine learning for healthcare revenue cycle analytics. The review focused on claim denial prediction, coding automation, payment delay forecasting, and prior authorization support. A PRISMA 2020-compliant review process was used, including structured database searching, dual screening, and domain-based narrative synthesis. Risk of bias was assessed using criteria adapted from PROBAST-AI, with attention to temporal validation, data leakage, and implementation relevance. The literature showed the greatest maturity in automated clinical coding and emerging but narrower evidence for claim denial prediction. Evidence for payment delay forecasting and prior authorization support was more limited, with few studies describing prospective implementation or measured operational impact. Machine learning shows promise for improving revenue cycle decision support, but most evidence remains retrospective and technically oriented. Deployment is constrained by data fragmentation, explainability requirements, workflow integration, and regulatory caution.
Journal of Health Informatics and Digital Systems
Review | Open access | 25 February 2024 | Article: 90

Artificial Intelligence in Smart Hospital Management: A Systematic Review of Command Centers, Real-Time Workflow Monitoring, Operational Dashboards, and Automated Decision Support Systems
Smart hospitals increasingly combine artificial intelligence, real-time data streams, operational dashboards, and automated decision support to coordinate care delivery. These systems aim to improve hospital throughput, staff efficiency, resource use, and patient safety. This systematic review synthesised evidence on AI technologies used in smart hospital management from 2017 to 2023. The review focused on command centers, real-time workflow monitoring, operational dashboards, and automated decision support systems. A PRISMA 2020-compliant review process was used, including structured database searching, dual screening, and narrative synthesis. Extracted data covered study characteristics, AI methods, deployment maturity, data sources, integration patterns, and reported operational impact. The evidence base was concentrated on hospital command centers, predictive dashboards, and patient-flow analytics. Real-time workflow monitoring and automated decision support were less mature, and prospective evaluations of operational or clinical impact were uncommon. AI-enabled smart hospital management is technologically promising but remains unevenly implemented and weakly evaluated. Current evidence supports cautious adoption, local validation, and stronger evaluation designs before claims of sustained operational transformation are accepted.
Journal of Health Informatics and Digital Systems
Review | Open access | 25 February 2024 | Article: 91

Artificial Intelligence for Healthcare Quality Improvement from 2017 to 2024: A Systematic Review of Predictive Models for Safety Events, Care Gaps, Adverse Outcomes, and Performance Monitoring
Healthcare quality improvement increasingly relies on routinely collected data to identify preventable harm, missed care opportunities, adverse outcomes, and variation in performance. Artificial intelligence predictive models may support earlier detection of quality risks and enable more proactive monitoring than retrospective audits alone. This systematic review examined artificial intelligence predictive models for healthcare quality improvement from 2017 to 2024. The review focused on patient safety events, care gaps, adverse clinical outcomes, and performance monitoring systems. A PRISMA 2020-compliant search was conducted across PubMed, Scopus, Web of Science, and IEEE Xplore for peer-reviewed English-language studies published from 2017 through 2024. Dual screening, structured data extraction, risk-of-bias assessment, and narrative synthesis were used. The evidence base showed growing use of machine learning for pressure injuries, sepsis, readmission, mortality, ICU transfer, and continuous monitoring. However, most studies remained retrospective model-development or validation studies, while fewer described deployment within formal quality improvement workflows. Technical progress in predictive modelling for quality improvement is substantial, but evidence of sustained improvement in care processes, safety outcomes, or organisational performance remains limited. Stronger prospective evaluation and clearer integration with improvement methods are needed.
Journal of Health Informatics and Digital Systems
Review | Open access | 25 February 2025 | Article: 104

Artificial Intelligence for Healthcare Equity Analytics from 2017 to 2024: A Systematic Review of Bias Detection, Fairness-Aware Prediction, Disparity Monitoring, and Algorithmic Accountability in Health Systems
Artificial intelligence models are increasingly used to support healthcare decision-making, resource allocation, clinical triage, population health management, and quality improvement. Without explicit equity assessment, these tools may reproduce, obscure, or scale existing disparities across racial, ethnic, sex, gender, socioeconomic, and geographic groups. This systematic review examined artificial intelligence approaches for healthcare equity analytics from 2017 to 2024. The review focused on bias detection, fairness-aware prediction, disparity monitoring, and algorithmic accountability in health systems. A PRISMA 2020-compliant search was conducted across PubMed, Scopus, Web of Science, and IEEE Xplore for peer-reviewed English-language studies published between 2017 and 2024. Eligible records were screened by two reviewers, and findings were synthesised narratively by equity task, method type, clinical application, fairness metric, and implementation context. The evidence base showed increasing attention to bias detection and fairness-aware algorithm design, especially in clinical risk prediction, diagnostic imaging, and population health management. Disparity monitoring systems and accountability structures were less frequently evaluated in deployed health system environments and were commonly described as governance recommendations, audit frameworks, or pilot-stage approaches. The technical foundations for equitable artificial intelligence in healthcare are advancing, but translation into operational health system practice remains limited. The strongest evidence concerns bias measurement, whereas evidence that fairness interventions reduce real-world health disparities remains nascent.
Journal of Health Informatics and Digital Systems
Review | Open access | 25 February 2025 | Article: 106

Generative Artificial Intelligence for Healthcare Administration: A Systematic Review of Applications in Documentation Support, Operational Reporting, Patient Communication, Governance Dashboards, and Workflow Automation
Healthcare administration is document-intensive, communication-heavy, and increasingly dependent on digital systems that require timely synthesis of clinical and operational information. Generative artificial intelligence has been proposed as a potential means of reducing administrative workload across documentation, reporting, patient communication, governance, and workflow coordination. This systematic review examined applications of generative artificial intelligence across five healthcare administrative domains: documentation support, operational reporting, patient communication, governance dashboards, and workflow automation. The review aimed to characterize reported use cases, model types, evaluation approaches, implementation barriers, and evidence maturity from 2017 to 2025. A PRISMA 2020-compliant search strategy was applied to PubMed, Scopus, IEEE Xplore, and Web of Science for studies published between January 1, 2017, and December 31, 2025. Screening was conducted in duplicate, and eligible studies were synthesized narratively by administrative domain. Documentation support was the most mature domain, particularly for clinical summarization, discharge summaries, patient-message drafting, and document classification. Operational reporting and governance dashboards were emerging areas, while patient communication and workflow automation showed diverse prototypes but limited prospective validation. Common challenges included hallucination, privacy, bias, regulatory uncertainty, integration burden, and limited evidence of real-world administrative impact. Generative artificial intelligence appears technically capable of supporting multiple healthcare administrative tasks, but evidence remains uneven across domains. Real-world impact, safety, scalability, and governance require stronger evaluation before these systems can be relied upon for high-stakes administrative decision-making.
Journal of Health Informatics and Digital Systems
Review | Open access | 25 February 2026 | Article: 121

Artificial Intelligence for Care Navigation and Patient Access: A Systematic Review of Scheduling Optimization, Referral Management, Eligibility Screening, Digital Front-Door Tools, and Follow-Up Coordination
Patient access to timely, appropriate care remains a persistent challenge for health systems, affecting clinical continuity, patient experience, and operational performance. Artificial intelligence has been proposed as a means of automating and optimizing navigation functions from scheduling to follow-up coordination. This systematic review examined artificial intelligence applications for care navigation and patient access across scheduling optimization, referral management, eligibility screening, digital front-door tools, and follow-up coordination. The review also assessed implementation maturity, evaluation approaches, and equity-related reporting. A PRISMA 2020-compliant search was conducted across PubMed, Scopus, IEEE Xplore, and Web of Science for publications from 2017 through 2025. Dual screening, structured data extraction, risk-of-bias assessment, and narrative synthesis were used to characterize the evidence. The literature was concentrated in scheduling optimization, particularly no-show prediction and operational appointment management, and in digital front-door tools such as symptom checkers and triage chatbots. Referral and eligibility applications were emerging, while follow-up coordination models often overlapped with readmission and care-transition prediction. Few studies reported prospective implementation, comparative deployment outcomes, or equity impacts. Artificial intelligence-driven patient access tools appear technically robust for isolated tasks, but evidence that they improve integrated, end-to-end navigation remains limited. The field requires stronger prospective evaluation, equity assessment, and implementation reporting.
Journal of Health Informatics and Digital Systems
Review | Open access | 25 February 2026 | Article: 123

Agentic Artificial Intelligence in Healthcare Systems: A Systematic Review of Autonomous Discharge Coordination, Task Routing, Human Oversight, Safety Guardrails, and Workflow Accountability
Agentic artificial intelligence systems—those capable of planning, executing, adapting, and learning across operational tasks—are beginning to influence healthcare administrative workflows. Their emergence raises important questions about autonomy, safety, oversight, and accountability in hospital systems. This systematic review examined the development and deployment of agentic AI in healthcare operations from 2017 to 2026. The review focused on autonomous discharge coordination, task routing, human oversight, safety guardrails, and workflow accountability. A PRISMA 2020–aligned search was conducted across PubMed, Scopus, IEEE Xplore, and Web of Science. Studies were screened by two reviewers, and eligible records were synthesised narratively according to task type, agent capability, oversight model, safety mechanism, and deployment maturity. The evidence base was nascent, heterogeneous, and dominated by predictive, prototype, implementation, and early deployment studies. Most systems supported discharge planning, workflow prediction, task prioritisation, or operational decision support rather than fully autonomous execution. Agentic AI has substantial potential to improve hospital operations, especially in discharge coordination and workflow routing. However, real-world deployment requires stronger safety engineering, prospective evaluation, explicit human oversight, and auditable accountability structures.
Journal of Health Informatics and Digital Systems
Review | Open access | 20 July 2026 | Article: 139

Artificial Intelligence for Digital Patient Communication: A Systematic Review of Portal Message Triage, Chatbot Support, Care Navigation, Automated Response Drafting, and Patient Engagement Analytics
Asynchronous digital communication with patients has become a routine component of modern healthcare delivery. The rapid growth of patient portals, chatbots, and digital front-door tools has created opportunities for more responsive care, while also increasing communication workload for clinical teams. This systematic review examined artificial intelligence applications in digital patient communication from 2017 to 2026. The review focused on portal message triage, chatbot support, care navigation, automated response drafting, and patient engagement analytics. A PRISMA 2020-compliant review was conducted using structured searches of PubMed, Scopus, IEEE Xplore, and Web of Science. Records were screened by two reviewers, with data extracted on communication domain, AI approach, clinical setting, evaluation strategy, safety reporting, and implementation maturity. The literature was dominated by studies of chatbot support and portal message triage, with a growing body of work on large language model-enabled response drafting. Care navigation and patient engagement analytics were less frequently evaluated, and most studies emphasized technical performance, user satisfaction, or feasibility rather than health outcomes or workload reduction in real-world settings. AI for patient communication appears technically promising in isolated tasks, particularly message classification, chatbot interaction, and draft response generation. However, evidence remains limited regarding safe, equitable, and effective deployment across integrated communication workflows.
Journal of Health Informatics and Digital Systems
Review | Open access | 20 July 2026 | Article: 141
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AI-driven Diagnostics Artificial Intelligence in Health Informatics Artificial Intelligence in Healthcare Big Data in Healthcare Clinical Data Mining Clinical Decision Support Systems Clinical Informatics Computer Vision Connected Health Systems Deep Learning Digital Health Digital Healthcare Innovation Digital Transformation in Healthcare Electronic Health Records Ethical AI in Healthcare Explainable AI Health Data Analytics Health Data Privacy Health Informatics Health Information Management Health Information Systems Health System Optimization Health Technology Assessment Healthcare Data Science Healthcare Informatics Healthcare Information Security Healthcare Management Healthcare Management Information Systems Intelligent Medical Systems Internet of Medical Things (IoMT) Interoperability in Healthcare Systems Machine Learning Medical Data Analytics Medical Data Management Medical Imaging Mobile Health (mHealth) Natural Language Processing Precision Medicine Predictive Analytics Remote Patient Monitoring Smart Healthcare Systems Telemedicine Wearable Health Technologies e-Health




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