Self-Supervised Graph Representation Learning for Predicting Drug Repurposing Candidates for Rare Pediatric Cancers Using Protein-Protein Interaction Networks and Gene Expression Data

cirpublications.com-LLPz-1790880686-z662784540 1790880686 Clinical Intelligence Research Press info@cirpublications.com Clinical Intelligence Research Press Journal of Artificial Intelligence for Healthcare Systems J. Artif. Intell. Healthc. Syst. 3149-8981 2025 4 2 Self-Supervised Graph Representation Learning for Predicting Drug Repurposing Candidates for Rare Pediatric Cancers Using Protein-Protein Interaction Networks and Gene Expression Data Luis Fernandez Marta Ruiz Sergio Navarro 2025 10.68159/z662784540 https://cirpublications.com/pub/journal/1/article/z662784540 Zeng X, Zhu S, Liu X, Zhou Y, Nussinov R, Cheng F, et al. deepDR: a network based deep learning approach to in silico drug repositioning. Bioinformatics. 2019;35(24):5191-8. Himmelstein DS, Lizee A, Hessler C, Brueggeman L, Chen SL, Hadley D, et al. Systematic integration of biomedical knowledge prioritizes drugs for repurposing. Elife. 2017;6:e26726. Zitnik M, Agrawal M, Leskovec J. 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