TY - JOUR T1 - Parameter-Efficient Fine-Tuning of Large Language Models for Automated Discharge Summary Generation from Daily Progress Notes and Laboratory Results AU - Anna Svensson AU - Erik Lindberg JF - Journal of Artificial Intelligence for Healthcare Systems JO - J. Artif. Intell. Healthc. Syst. SN - 3149-8981 Y1 - 2025 VL - 4 IS - 1 SP - 101 N2 - Hospital discharge summaries are critical for care transitions, directly impacting readmission prevention and medication reconciliation, yet physicians spend 15-30 minutes per patient drafting these documents, contributing substantially to documentation burden and professional burnout. Manual summarization of daily progress notes and laboratory results is repetitive, time-consuming, and error-prone, as clinicians must sift through lengthy unstructured notes across multiple hospital days while identifying salient events and trends. We propose a large language model with parameter-efficient fine-tuning for automated discharge summary generation that processes chronologically ordered daily progress notes alongside time-series laboratory results to produce structured discharge documentation. The framework consists of a base LLM augmented with LoRA adapters, a progress note encoder for section segmentation, a laboratory result integrator that computes trend indicators, and a summary generator that produces sectioned discharge output. Parameter-efficient fine-tuning enables domain adaptation to clinical text with minimal computational resources, preserving patient-specific information while reducing hallucination through retrieval of key factual details from the input notes. This framework offers a practical pathway to reduced documentation burden and improved discharge quality, with potential for widespread deployment across health systems given the modest computational requirements of PEFT approaches. UR - https://cirpublications.com/y427182552 ER -