TY - JOUR T1 - A Multi-Source Public Health Surveillance Intelligence Mesh for Outbreak-Aware Systems AU - Yousef Al-Qahtani AU - Fahad Al-Salem AU - Abdullah Al-Harbi JF - Journal of Artificial Intelligence for Healthcare Systems JO - J. Artif. Intell. Healthc. Syst. SN - 3149-8981 Y1 - 2026 VL - 5 IS - 1 SP - 47 N2 - Traditional public health surveillance often operates within fragmented data silos, leading to delayed outbreak recognition and suboptimal clinical responses. This conceptual systems research article presents the multi-source public health surveillance intelligence mesh (MPSIM). This original architectural paradigm interconnects heterogeneous data ecosystems into a resilient, outbreak-aware intelligence fabric. MPSIM synthesizes multi-modal inputs from electronic health records, genomic repositories, environmental sensors, and social-determinant streams through a theoretically defined mesh topology that supports continuous intelligence propagation and adaptive governance.The framework introduces a five-layer stratified architecture with a unique polyadic feedback topology enabling bidirectional drift correction and resource orchestration. Three interpretive conceptual formulas are advanced to model risk propagation, decision confidence, and governance load, furnishing system designers with abstract yet operationalizable constructs.MPSIM is positioned as a blueprint for next-generation, outbreak-aware healthcare systems that embed surveillance intelligence directly into clinical workflows while satisfying stringent governance and interoperability requirements. The architecture prioritizes theoretical scalability, ethical oversight, and seamless multi-source fusion to advance proactive containment strategies across diverse deployment environments. UR - https://cirpublications.com/v978476617 ER -