TY - JOUR
T1 - Dynamic Comorbidity Graphs for Continual Population Stratification: A Longitudinal Network Modeling Framework
AU - Chen Hao
AU - Liu Fang
AU - Zhao Lin
JF - Journal of Health Informatics and Digital Systems
JO - J. Health Inform. Digit. Syst.
SN - 3149-8973
Y1 - 2023
VL - 3
IS - 1
SP - 23
N2 - The escalating complexity of multimorbidity in aging populations necessitates advanced analytical frameworks for real-time patient stratification. This conceptual manuscript introduces a novel longitudinal network modeling approach centered on dynamic comorbidity graphs (DCGs), which enable continual population stratification through adaptive graph-based representations of electronic health records (EHRs). By integrating temporal disease trajectories, the framework facilitates proactive clinical decision-making without relying on empirical datasets or model training. Key components include graph construction algorithms that evolve with patient cohorts, comorbidity linkage mechanisms for risk propagation, and stratification pipelines that support interoperability across healthcare systems. Theoretical formulas are proposed to interpret risk propagation dynamics, decision confidence thresholds, and governance loads in deployment environments. The architecture emphasizes clinical workflow integration, addressing challenges in data modality heterogeneity and governance constraints. Through literature synthesis, we highlight synergies with existing AI governance systems, EHR intelligence ecosystems, and decision support pipelines. This framework advances healthcare analytics infrastructures by providing a scalable, theoretical foundation for managing longitudinal multimorbidity patterns, ultimately enhancing population health management in diverse clinical settings. Potential implications include improved resource allocation and reduced monitoring burdens in AI-assisted healthcare delivery.
UR - https://cirpublications.com/u384500918
ER -